{"title":"\u30a2\u30a6\u30ea\u30f3\u30c8\u30ea\u30ab\u30eb\u30dc\u30f3\u9178\u306f\u30b1\u30e2\u30ab\u30a4\u30f3\u3092\u4ecb\u3057\u305f\u75c5\u539f\u6027\u7d30\u80de\u306e\u79fb\u52d5\u304a\u3088\u3073\u6d78\u6f64\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u5b9f\u9a13\u7684\u81ea\u5df1\u514d\u75ab\u6027\u8133\u810a\u9ac4\u708e\u3092\u6539\u5584\u3059\u308b","provider_name":"Hatena Blog","image_url":null,"blog_url":"https://autoimmune.hateblo.jp/","type":"rich","author_name":"autoimmune-research","author_url":"https://blog.hatena.ne.jp/autoimmune-research/","url":"https://autoimmune.hateblo.jp/entry/2022/05/26/153750","width":"100%","published":"2022-05-26 15:37:50","blog_title":"Autoimmunology Research","categories":[],"provider_url":"https://hatena.blog","version":"1.0","html":"<iframe src=\"https://hatenablog-parts.com/embed?url=https%3A%2F%2Fautoimmune.hateblo.jp%2Fentry%2F2022%2F05%2F26%2F153750\" title=\"\u30a2\u30a6\u30ea\u30f3\u30c8\u30ea\u30ab\u30eb\u30dc\u30f3\u9178\u306f\u30b1\u30e2\u30ab\u30a4\u30f3\u3092\u4ecb\u3057\u305f\u75c5\u539f\u6027\u7d30\u80de\u306e\u79fb\u52d5\u304a\u3088\u3073\u6d78\u6f64\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u5b9f\u9a13\u7684\u81ea\u5df1\u514d\u75ab\u6027\u8133\u810a\u9ac4\u708e\u3092\u6539\u5584\u3059\u308b - Autoimmunology Research\" class=\"embed-card embed-blogcard\" scrolling=\"no\" frameborder=\"0\" style=\"display: block; width: 100%; height: 190px; max-width: 500px; margin: 10px 0px;\"></iframe>","description":"\u591a\u767a\u6027\u786c\u5316\u75c7\u304a\u3088\u3073\u305d\u306e\u52d5\u7269\u30e2\u30c7\u30eb\u3067\u3042\u308b\u5b9f\u9a13\u7684\u81ea\u5df1\u514d\u75ab\u6027\u8133\u810a\u9ac4\u708e\uff08EAE\uff09\u306f\u3001CNS\u306e\u514d\u75ab\u4ecb\u5728\u6027\u8131\u9ac4\u3068\u795e\u7d4c\u5909\u6027\u3092\u7279\u5fb4\u3068\u3059\u308b\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3067\u3042\u308b\u3002 CD4(+)T\u7d30\u80de\u3001\u7279\u306bTh1\u304a\u3088\u3073Th17\u4e9c\u96c6\u56e3\u306e\u904e\u5270\u6d3b\u6027\u5316\u304c\u3053\u306e\u75be\u60a3\u306e\u76f4\u63a5\u7684\u306a\u539f\u56e0\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002 ATA\uff08\u30a2\u30a6\u30ea\u30f3\u30c8\u30ea\u30ab\u30eb\u30dc\u30f3\u9178\uff09\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea-\u6838\u9178\u76f8\u4e92\u4f5c\u7528\u963b\u5bb3\u5264\u3067\u3042\u308a\u3001Th\u7d30\u80de\u306e\u5206\u5316\u306b\u91cd\u8981\u306aJAK/STAT\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u7d4c\u8def\u3092\u906e\u65ad\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002 \u672c\u7814\u7a76\u3067\u306f\u3001ATA\u6295\u4e0e\u304cEAE\u306e\u81e8\u5e8a\u7684\u30b9\u30b3\u30a2\u3092\u6709\u610f\u306b\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u305f\u304c\u3001in vitro\u3067\u306eTh1\u304a\u3088\u3073Th17\u7d30\u80de\u306e\u5206\u5316\u3092\u76f4\u63a5\u963b\u5bb3\u3059\u308b\u3053\u3068\u306f\u306a\u304b\u3063\u305f\u3002 ATA\u306f\u3001\u767a\u75c7\u524d\u306eEAE\u30de\u2026","height":"190"}