{"title":"\u3042\u308c\u306f\u307e\u3055\u306b","type":"rich","height":"190","html":"<iframe src=\"https://hatenablog-parts.com/embed?url=https%3A%2F%2Fazarashi-panda.hatenablog.com%2Fentry%2F2025%2F12%2F25%2F054342\" title=\"\u3042\u308c\u306f\u307e\u3055\u306b - Azarashi_Panda\u306e\u65e5\u8a18\" class=\"embed-card embed-blogcard\" scrolling=\"no\" frameborder=\"0\" style=\"display: block; width: 100%; height: 190px; max-width: 500px; margin: 10px 0px;\"></iframe>","url":"https://azarashi-panda.hatenablog.com/entry/2025/12/25/054342","version":"1.0","categories":["\u4f4e\u5206\u5b50\u5275\u85acTIPS"],"author_name":"Azarashi_Panda","provider_name":"Hatena Blog","published":"2025-12-25 05:43:42","blog_title":"Azarashi_Panda\u306e\u65e5\u8a18","image_url":"https://cdn-ak.f.st-hatena.com/images/fotolife/A/Azarashi_Panda/20251225/20251225053537.png","blog_url":"https://azarashi-panda.hatenablog.com/","width":"100%","provider_url":"https://hatena.blog","author_url":"https://blog.hatena.ne.jp/Azarashi_Panda/","description":"\u3042\u308c\u306f\u307e\u3055\u306b #souyakuAC2025 Kymera\u793e\u306eCDK2 degrader\u304a\u3088\u3073BMS\u793e\u306eBCL6 degrader\u306e\u5275\u88fd\u3002\u305d\u308c\u305e\u308c\u5b66\u3073\u306b\u306a\u308b\u691c\u8a0e\u5185\u5bb9\u3060\u304c\u3001\u5171\u901a\u3057\u3066\u6ce8\u76ee\u3057\u305f\u3044\u306e\u306f\u3001\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u3068CRBN\u304c\u30bf\u30f3\u30d1\u30af\u8cea\u9593\u76f8\u4e92\u4f5c\u7528\u3092\u5f62\u6210\u3057\u3066\u3044\u308b\u70b9\u3002\u4ee5\u524d\u306b\u30a2\u30b9\u30c6\u30e9\u30b9\u306eKras degrader\u306e\u8a18\u4e8b\u3067\u3082\u8ff0\u3079\u305f\u304c\u3001\u6700\u521d\u306b\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u3068E3 ligase\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u9593\u76f8\u4e92\u4f5c\u7528\u3092\u4e88\u6e2c\u3057\u3066\u3001\u5316\u5408\u7269\u306f\u5f8c\u304b\u3089\u305d\u306e\u9593\u306b\u30cf\u30de\u308b\u3088\u3046\u306b\u30c7\u30b6\u30a4\u30f3\u3059\u308b\u3053\u3068\u3082\u3067\u304d\u308b\u304b\u3082\u3002 \u304b\u305f\u3084\uff13\u4eba\uff01\uff01 \u3042\u308c\u306f\u307e\u3055\u306b \u5408\u4f53\uff01\uff01\uff01 \u3010Kymera\u793e\u306eCDK2 degrader\u3011 Discovery of Selective an\u2026"}