{"published":"2017-02-01 23:31:38","author_name":"Bethelgeuse","provider_name":"Hatena Blog","blog_title":"Bethelgeuse\u2019s blog","categories":[],"author_url":"https://blog.hatena.ne.jp/Bethelgeuse/","type":"rich","title":"\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306b\u3088\u308b\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5 (PD) \u306e\u30ea\u30b9\u30af\u907a\u4f1d\u5b50\u306e\u540c\u5b9a","url":"https://bethelgeuse.hatenablog.com/entry/2017/02/01/233138","html":"<iframe src=\"https://hatenablog-parts.com/embed?url=https%3A%2F%2Fbethelgeuse.hatenablog.com%2Fentry%2F2017%2F02%2F01%2F233138\" title=\"\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306b\u3088\u308b\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5 (PD) \u306e\u30ea\u30b9\u30af\u907a\u4f1d\u5b50\u306e\u540c\u5b9a - Bethelgeuse\u2019s blog\" class=\"embed-card embed-blogcard\" scrolling=\"no\" frameborder=\"0\" style=\"display: block; width: 100%; height: 190px; max-width: 500px; margin: 10px 0px;\"></iframe>","image_url":null,"version":"1.0","height":"190","width":"100%","description":"Genome Biology\u3088\u308a\u3002\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306f\u3001\u5168\u30a8\u30af\u30bd\u30f3\u89e3\u6790\u3068\u3082\u3088\u3070\u308c\u3001\u907a\u4f1d\u5b50\u306e\u30a8\u30af\u30bd\u30f3\u90e8\u5206\u3092\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3059\u308b\u65b9\u6cd5\u3067\u3059\u30021148\u540d\u306ePD\u60a3\u8005\u3068503\u540d\u306e\u5065\u5e38\u8005\u3067\u3001\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u304c\u5b9f\u65bd\u3055\u308c\u300127\u500b\u306e\u907a\u4f1d\u5b50\u306b\u3064\u3044\u3066loss-of-function\u306b\u3064\u306a\u304c\u308b\u30d0\u30ea\u30a2\u30f3\u30c8\u304cPD\u60a3\u8005\u3067\u898b\u51fa\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u907a\u4f1d\u5b50\u306b\u95a2\u3057\u3066\u3001\u3055\u3089\u306b\u7d30\u80de\u3084\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u30e2\u30c7\u30eb\u3092\u4f7f\u3063\u3066RNAi\u306b\u3088\u308b\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u30015\u500b\u306e\u907a\u4f1d\u5b50 (GPATCH2L, UHRF1BP1L, PTPRH, ARSB, VPS13C) \u304c\u75c5\u614b\u3068\u6a5f\u80fd\u7684\u306b\u3082\u95a2\u4fc2\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002 Discovery and functional prioriti\u2026","provider_url":"https://hatena.blog","blog_url":"https://bethelgeuse.hatenablog.com/"}