{"published":"2012-05-30 03:59:00","version":"1.0","html":"<iframe src=\"https://hatenablog-parts.com/embed?url=https%3A%2F%2Fmedi.atsuhiro-me.net%2Fentry%2F2012%2F05%2F30%2F035900\" title=\"\u304c\u3093-p53\u307e\u3068\u3081 - \u307f\u30fc\u306e\u533b\u5b66\" class=\"embed-card embed-blogcard\" scrolling=\"no\" frameborder=\"0\" style=\"display: block; width: 100%; height: 190px; max-width: 500px; margin: 10px 0px;\"></iframe>","provider_name":"Hatena Blog","blog_title":"\u307f\u30fc\u306e\u533b\u5b66","height":"190","author_url":"https://blog.hatena.ne.jp/atsuhiro-me/","categories":["\u816b\u760d","\u307e\u3068\u3081"],"url":"https://medi.atsuhiro-me.net/entry/2012/05/30/035900","author_name":"atsuhiro-me","image_url":"http://cdn-ak.f.st-hatena.com/images/fotolife/a/atsuhiro-me/20151120/20151120221842.png","description":"p53-RB pathway\u306b\u3064\u3044\u3066\u7406\u89e3\u3057\u3084\u3059\u3044\u3088\u3046\u306b\u307e\u3068\u3081\u3066\u304a\u304d\u307e\u3059\uff0e \u7d30\u80de\u306fDNA\u640d\u50b7\u306a\u3069\u306b\u3088\u3063\u3066\u5e38\u306b\u30ac\u30f3\u7d30\u80de\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0ep53\u306f\u304c\u3093\u5316\u3092\u6291\u5236\u3059\u308b\u50cd\u304d\u304c\u3042\u308b\u306e\u3067\u304c\u3093\u6291\u5236\u907a\u4f1d\u5b50\u3068\u3082\u547c\u3070\u308c\u3066\u3044\u308b\uff0e\u304c\u3093\u306e\u6291\u5236\u65b9\u6cd5\u306f\u4e3b\u306b3\u3064\uff1a G1\u671f\u3067\u7d30\u80de\u5468\u671f\u3092\u6b62\u3081\u308b DNA\u4fee\u5fa9\u3092\u884c\u3046 \u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3059\u308b \u3067\u3042\u308b\uff0e p21\u306fCKI\u306e\u4e00\u7a2e\u3067\u3042\u308b\uff0eCKI\u306f cyclin-dependent kinase inhibitor\u306e\u7565\u3067CDK\u3092\u6291\u5236\u3059\u308b\uff0eCDK\u306f\u30b5\u30a4\u30af\u30ea\u30f3\u3068\u3068\u3082\u306b\u7d30\u80de\u5468\u671f\u3092\u9032\u3081\u308b\u4f5c\u7528\u304c\u3042\u308b\u306e\u3067p21\u304ccdk\u3092\u6291\u5236\u3059\u308b\u306e\u306f\u8003\u3048\u308c\u3070\u5206\u304b\u308b\uff0e RB\u306f \u7d30\u80de\u5468\u671f\u3092G1\u3067\u505c\u6b62\u3059\u308b\u50cd\u304d\u304c\u3042\u308b\uff0e\u3064\u307e\u308acdk\u3068\u53cd\u5bfe\u306e\u4f5c\u2026","blog_url":"https://medi.atsuhiro-me.net/","width":"100%","provider_url":"https://hatena.blog","type":"rich","title":"\u304c\u3093-p53\u307e\u3068\u3081"}