{"description":"Decanalization and the origin of complex disease. G Gibson nat revies genet 10:134-140 2009 \u30e2\u30c7\u30eb Common disease-common variant \u30e2\u30c7\u30eb \u96c6\u56e3\u306b\u304a\u3051\u308b\u983b\u5ea6\u304c\u591a\u578b\u57df(\uff11\uff05\u4ee5\u4e0a)\u306e\u591a\u578b\u304c\u75be\u60a3\u306e\u907a\u4f1d\u8981\u7d20\u306e\u4f55\u5206\u306e\u4e00\u304b\u7a0b\u5ea6\u306e\u5bc4\u4e0e\u3092\u3057\u3066\u3044\u308b\u3068\u3059\u308b\u30e2\u30c7\u30eb\u3002 Rare alleles of major effect \u30e2\u30c7\u30eb \u75be\u60a3\u306e\u983b\u5ea6\u306fcommmon\u3060\u304c\u3001\u305d\u306e\u907a\u4f1d\u7684\u80cc\u666f\u306f\u7570\u306a\u308a\u3001\u4f4e\u983b\u5ea6(\uff11\uff05\u672a\u6e80)\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u305d\u308c\u3092\u30db\u30e2\u3067\u6301\u3063\u305f\u308a\u3001\u7570\u306a\u308b\u5909\u7570\u306e\u30d8\u30c6\u30ed\u3060\u3063\u305f\u308a\u3059\u308b\u3053\u3068\u3067\u767a\u75c7\u3059\u308b\u3068\u3059\u308b\u30e2\u30c7\u30eb\u3002\u2026","provider_url":"https://hatena.blog","title":"Decanalization\u306b\u3088\u308b\u8907\u5408\u907a\u4f1d\u6027\u75be\u60a3\u306e\u8aac\u660e","html":"<iframe src=\"https://hatenablog-parts.com/embed?url=https%3A%2F%2Fryamada22.hatenablog.jp%2Fentry%2F20090328%2F1238278295\" title=\"Decanalization\u306b\u3088\u308b\u8907\u5408\u907a\u4f1d\u6027\u75be\u60a3\u306e\u8aac\u660e - ryamada\u306e\u907a\u4f1d\u5b66\u30fb\u907a\u4f1d\u7d71\u8a08\u5b66\u30e1\u30e2\" class=\"embed-card embed-blogcard\" scrolling=\"no\" frameborder=\"0\" style=\"display: block; width: 100%; height: 190px; max-width: 500px; margin: 10px 0px;\"></iframe>","height":"190","type":"rich","published":"2009-03-28 07:11:35","categories":["\u8ad6\u6587","\u75be\u60a3\u95a2\u9023\u907a\u4f1d\u5b50\u89e3\u6790","\u95a2\u9023\u89e3\u6790","\u6587\u732e","\u3071\u3089\u3071\u3089\u3081\u304f\u308b\u30b7\u30ea\u30fc\u30ba"],"width":"100%","url":"https://ryamada22.hatenablog.jp/entry/20090328/1238278295","blog_title":"ryamada\u306e\u907a\u4f1d\u5b66\u30fb\u907a\u4f1d\u7d71\u8a08\u5b66\u30e1\u30e2","version":"1.0","provider_name":"Hatena Blog","blog_url":"https://ryamada22.hatenablog.jp/","author_name":"ryamada22","image_url":null,"author_url":"https://blog.hatena.ne.jp/ryamada22/"}